Chapter 61 Epidemiology of Equine Infectious Disease

  1. Gordis L: Epidemiology. Philadelphia, 1996, Saunders.
  2. Dwyer RM, Garber LP, Traub-Dargatz JL, et al: Case-control study of factors associated with excessive proportions of early fetal losses associated with mare reproductive loss syndrome in central Kentucky during 2001. J Am Vet Med Assoc 222:613–619, 2003. PUBMED Abstract
  3. Cohen ND, Carey VJ, Donahue JG, et al: Case-control study of late-term abortions associated with mare reproductive loss syndrome in central Kentucky. J Am Vet Med Assoc 222:199–209, 2003. PUBMED Abstract
  4. Webb BA, Barney WE, Dahlman DL, et al: Eastern tent caterpillars (Malacosoma americanum) cause mare reproductive loss syndrome. J Insect Physiol 50:185–193, 2004. PUBMED Abstract
  5. Slovis NM: Clinical observations of the pericarditis syndrome. Session 1: Field and clinical observations on MRLS. 2002, Workshop on Mare Reproductive Loss.
  6. Latimer C: Endophthalmitis: a syndrome associated with mare reproductive loss syndrome? Session 1: Field and clinical observations on MRLS. 2002, Workshop on Mare Reproductive Loss.
  7. Cohen ND, Donahue JG, Carey VJ, et al: Case-control study of early-term abortions (early fetal losses) associated with mare reproductive loss syndrome in central Kentucky. J Am Vet Med Assoc 222:210–217, 2003. PUBMED Abstract
  8. Donahue JG, Sells S, Giles R, et al: Bacteria associated with mare reproductive loss syndrome: late fetal losses. Session 2: Laboratory correlates of MRLS. 2002, Workshop on Mare Reproductive Loss.
  9. Tobin T, Harkins JD, Roberts JF, et al: The mare reproductive loss syndrome and the eastern tent caterpillar. II. A toxicokinetic/clinical evaluation and a proposed pathogenesis: septic penetrating setae. J Appl Res Vet Med 2:142–158, 2004.
  10. Priddy T: Mare reproductive loss syndrome: weather data. 2001, University of Kentucky.
  11. Fitzgerald TD: The tent caterpillars. Ithaca, NY, 1995, Cornell University.
  12. Dwyer RM: Fitting the pieces of the puzzle: mare reproductive loss syndrome update. Equine Vet Educ 15:45–47, 2003.
  13. Schuler LA, Khaitsa ML, Dyer NW, et al: Evaluation of an outbreak of West Nile virus infection in horses: 569 cases (2002). J Am Vet Med Assoc 225:1084–1089, 2004. PUBMED Abstract
  14. Rossano MG, Kaneene JB, Marteniuk JV, et al: The seroprevalence of antibodies to Sarcocystis neurona in Michigan equids. Prev Vet Med 48:113–128, 2001. PUBMED Abstract
  15. Pitel PH, Lindsay DS, Caure S, et al: Reactivity against Sarcocystis neurona and Neospora by serum antibodies in healthy French horses from two farms with previous equine protozoal myeloencephalitis–like cases. Vet Parasitol 111:1–7, 2003. PUBMED Abstract
  16. Vardeleon D, Marsh AE, Thorne JG, et al: Prevalence of Neospora hughesi and Sarcocystis neurona antibodies in horses from various geographical locations. Vet Parasitol 95:273–282, 2001. PUBMED Abstract
  17. Baverud V, Gustafsson A, Franklin A, et al: Clostridium difficile: prevalence in horses and environment, and antimicrobial susceptibility. Equine Vet J 35:465–471, 2003. PUBMED Abstract
  18. Chanter N, Talbot NC, Newton JR, et al: Streptococcus equi with truncated M-proteins isolated from outwardly healthy horses. Microbiology (Reading) 146:1361–1369, 2000. PUBMED Abstract
  19. Fintl C, Dixon PM, Brazil TJ, et al: Endoscopic and bacteriological findings in a chronic outbreak of strangles. Vet Rec 147:480–484, 2000. PUBMED Abstract
  20. Newton JR, Verheyen K, Talbot NC, et al: Control of strangles outbreaks by isolation of guttural pouch carriers identified using PCR and culture of Streptococcus equi. Equine Vet J 32:515–526, 2000. PUBMED Abstract
  21. Verheyen K, Newton JR, Talbot NC, et al: Elimination of guttural pouch infection and inflammation in asymptomatic carriers of Streptococcus equi. Equine Vet J 32:527–532, 2000. PUBMED Abstract
  22. Borchers K, Wolfinger U, Ludwig H: Latency-associated transcripts of equine herpesvirus type 4 in trigeminal ganglia of naturally infected horses. J Gen Virol 80:2165–2171, 1999. PUBMED Abstract
  23. Smith DJ, Iqbal J, Purewal A, et al: In vitro reactivation of latent equid herpesvirus-1 from CD5+/CD8+ leukocytes indirectly by IL-2 or chorionic gonadotropin. J Gen Virol 79:2997–3004, 1998. PUBMED Abstract
  24. Borchers K, Wolfinger U, Lawrenz B, et al: Equine herpesvirus 4 DNA in trigeminal ganglia of naturally infected horses detected by direct in situ PCR. J Gen Virol 78:1109–1114, 1997. PUBMED Abstract
  25. Rizvi SM, Slater JD, Wolfinger U, et al: Detection and distribution of equine herpesvirus 2 DNA in the central and peripheral nervous systems of ponies. J Gen Virol 78:1115–1118, 1997. PUBMED Abstract
  26. Edington N, Welch HM, Griffiths L: The prevalence of latent equid herpesviruses in the tissues of 40 abattoir horses. Equine Vet J 26:140–142, 1994. PUBMED Abstract
  27. Slater JD, Borchers K, Thackray AM, et al: The trigeminal ganglion is a location for equine herpesvirus 1 latency and reactivation in the horse. J Gen Virol 75:2007–2016, 1994. PUBMED Abstract
  28. Welch HM, Bridges CG, Lyon AM, et al: Latent equid herpesviruses 1 and 4: detection and distinction using the polymerase chain reaction and co-cultivation from lymphoid tissues. J Gen Virol 73:261–268, 1992. PUBMED Abstract
  29. Edington N, Bridges CG, Huckle A: Experimental reactivation of equid herpesvirus 1 (EHV 1) following the administration of corticosteroids. Equine Vet J 17:369–372, 1985. PUBMED Abstract
  30. Thrusfield M: Veterinary epidemiology, ed 2, London, 1995, Blackwell Science.
  31. Rothman KJ, Greenland S: Modern epidemiology, ed 2, Philadelphia, 1998, Lippincott-Raven.
  32. Fine PE: Herd immunity: history, theory, practice. Epidemiol Rev 15:265–302, 1993. PUBMED Abstract
  33. Sebastian M, Gantz MG, Tobin T, et al: The mare reproductive loss syndrome and the eastern tent caterpillar: a toxicokinetic/statistical analysis with clinical, epidemiologic, and mechanistic implications. Vet Ther 4:324–339, 2003. PUBMED Abstract
  34. Hayes CG: West Nile fever. In Monath TP, editor: The arboviruses: epidemiology and ecology, Boca Raton, FL, 1989, CRC Press, pp 59–88.
  35. Hubalek Z, Halouzka J, Juricova Z: West Nile fever in Czechland. Emerg Infect Dis 5:594–595, 1999. PUBMED Abstract
  36. Romi R, Pontuale G, Ciufolini MG, et al: Potential vectors of West Nile virus following an equine disease outbreak in Italy. Med Vet Entomol 18:14–19, 2004. PUBMED Abstract
  37. Work TH, Hurlbut HS, Taylor RM: Indigenous wild birds of the Nile delta as potential West Nile virus circulating reservoirs. Am J Trop Med Hyg 4:872–888, 1955. PUBMED Abstract
  38. Abbassy MM, Osman M, Marzouk AS: West Nile (Flaviviridae: Flavivirus) in experimentally infected Argas ticks (Argasidae). Am J Trop Med Hyg 48:726–737, 1993. PUBMED Abstract
  39. Lawrie CH, Uzcategui NY, Gould EA, et al: Ixodid and argasid tick species and West Nile virus. Emerg Infect Dis 10:653–657, 2004. PUBMED Abstract
  40. US Department of Agriculture, Animal and Plant Health Inspection Service: “Hot Issues”: West Nile virus. Available at Accessed March 2005.
  41. Saville WJ, Reed SM, Morley PS, et al: Analysis of risk factors for the development of equine protozoal myeloencephalitis in horses. J Am Vet Med Assoc 217:1174–1180, 2000. PUBMED Abstract
  42. Meijer WG, Prescott JF: Rhodococcus equi. Vet Res 35:383–396, 2004. PUBMED Abstract
  43. Dohoo I, Martin W, Stryhn H: Veterinary epidemiologic research. Charlottetown, 2003, AVC.
  44. Trock SC, Meade BJ, Glaser AL, et al: West Nile virus outbreak among horses in New York State, 1999 and 2000. Emerg Infect Dis 7:745–747, 2001. PUBMED Abstract
  45. Estrada-Franco JG, Navarro-Lopez R, Beasley DWC, et al: West Nile virus in Mexico: evidence of widespread circulation since July 2002. Emerg Infect Dis 9:1604–1607, 2003. PUBMED Abstract
  46. Dauphin G, Zientara S, Zeller H, et al: West Nile: worldwide current situation in animals and humans. Comp Immunol Microbiol Infect Dis 27:343–355, 2004. PUBMED Abstract
  47. Zeller HG, Schuffenecker I: West Nile virus: an overview of its spread in Europe and the Mediterranean basin in contrast to its spread in the Americas. Eur J Clin Microbiol Infect Dis 23:147–156, 2004. PUBMED Abstract
  48. Marlenee NL, Lorono-Pino MA, Beaty BJ, et al: Detection of antibodies to West Nile and Saint Louis encephalitis viruses in horses. Salud Publica Mexico 46:373–375, 2004. PUBMED Abstract
  49. Salazer PL, et al: Outcome of equids with clinical signs of West Nile virus infection and factors associated with death. J Am Vet Med Assoc 225:267–274, 2004.
  50. US Department of Agriculture, Animal and Plant Health Inspection Service: Equine Program information: West Nile virus in 2004. (accessed February 2005).
  51. World Organization for Animal Health (OIE): Update on avian influenza in animals in Asia (type H5). Available at INFLUENZA/A_AI-Asia.htm. Accessed February 2005.
  52. McQueen JL, Davenport FM, Keeran RJ, et al: Studies of equine influenza in Michigan, 1963. II. Epizootiology. Am J Epidemiol 83:280–286, 1966. PUBMED Abstract
  53. Rose MA: Respiratory virus infections in man and animals: equine influenza viruses isolated at Cambridge in 1963 and 1965. Proc R Soc Med 59:51–52, 1966. PUBMED Abstract
  54. Scholtens RG, Steele JH, Dowdle WR, et al: U.S. epizootic of equine influenza, 1963. Public Health Rep 79:393–402, 1964. PUBMED Abstract
  55. Kitchen RH, Kehler WH, Henthorne JC: The 1963 equine influenza epizootic. J Am Vet Med Assoc 143:1108–1110, 1963. PUBMED Abstract
  56. Mare CJ: Vesicular stomatitis: ecology of the disease in the USA. In Equine infectious diseases VIII. Proceedings of the Eighth International Conference, Dubai, 1998, pp 243–245.
  57. Schmidtmann ET, Tabachnick WJ, Hunt GJ, et al: 1995 epizootic of vesicular stomatitis (New Jersey serotype) in the western United States: an entomologic perspective. J Med Entomol 36:1–7, 1999. PUBMED Abstract
  58. McCluskey BJ, Hurd HS, Mumford EL: Review of the 1997 outbreak of vesicular stomatitis in the western United States. J Am Vet Med Assoc 215:1259–1262, 1999. PUBMED Abstract
  59. Oldruitenborgh-Oosterbaan MM, Schipper FC, Goehring LS, et al: Pleasure horses with neurological signs: EHV1-infection or mycotoxin intoxication? Tijdschrift Diergeneeskunde 124:679–681, 1999.
  60. Morley PS, Townsend HGG, Bogdan JR, et al: Descriptive epidemiologic study of disease associated with influenza virus infections during three epidemics in horses. J Am Vet Med Assoc 216:535–544, 2000. PUBMED Abstract
  61. Kim LM, Morley PS, Traub-Dargatz JL, et al: Factors associated with Salmonella shedding among equine colic patients at a veterinary teaching hospital. J Am Vet Med Assoc 218:740–748, 2001. PUBMED Abstract
  62. Daniel WW: Biostatistics: a foundation for analysis in the health sciences, ed 7, New York, 1999, Wiley.
  63. Daft BM, Barr BC, Gardner IA, et al: Sensitivity and specificity of Western blot testing of cerebrospinal fluid and serum for diagnosis of equine protozoal myeloencephalitis in horses with and without neurologic abnormalities. J Am Vet Med Assoc 221:1007–1013, 2002. PUBMED Abstract
  64. Duarte PC, Daft BM, Conrad PA, et al: Evaluation and comparison of an indirect fluorescent antibody test for detection of antibodies to Sarcocystis neurona, using serum and cerebrospinal fluid of naturally and experimentally infected, and vaccinated horses. J Parasitol 90:379–386, 2004. PUBMED Abstract
  65. Ostlund EN, Crom RL, Pedersen DD, et al: Equine West Nile encephalitis, United States. Emerg Infect Dis 7:665–669, 2001. PUBMED Abstract
  66. Durham AE, Smith KC, Newton JR: An evaluation of diagnostic data in comparison to the results of liver biopsies in mature horses. Equine Vet J 35:554–559, 2003. PUBMED Abstract
  67. Greiner M, Gardner IA: Epidemiologic issues in the validation of veterinary diagnostic tests. Prev Vet Med 45:3–22, 2000. PUBMED Abstract
  68. Greiner M, Gardner IA: Application of diagnostic tests in veterinary epidemiologic studies. Prev Vet Med 45:43–59, 2000. PUBMED Abstract
  69. Schwabe C: Veterinary medicine and human health, ed 3, Baltimore, 1984, Williams & Wilkins.
  70. International Society for Infectious Diseases: West Nile virus updates 2004. ProMed-mail archives, 2005.
  71. US Department of Agriculture, Animal and Plant Health Inspection Service: Foreign Animal Disease Report, 1998, p 66.
  72. Bridges VE, McCluskey BJ, Salman MD, et al: Review of the 1995 vesicular stomatitis outbreak in the western United States. J Am Vet Med Assoc 211:556–560, 1997. PUBMED Abstract
  73. Hurd HS, McCluskey BJ, Mumford EL: Management factors affecting the risk for vesicular stomatitis in livestock operations in the western United States. J Am Vet Med Assoc 215:1263–1268, 1999. PUBMED Abstract