Chapter 10 Ocular Infections

  1. Moore CP, Heller N, Majors LJ, et al: Prevalence of ocular microorganisms in hospitalized and stabled horses. Am J Vet Res 49(6):773–777, 1988. PUBMED Abstract
  2. Whitley RD, Moore CP: Microbiology of the equine eye in health and disease. Vet Clin North Am 6(3):451–466, 1984. PUBMED Abstract
  3. Whitley RD, Burgess EC, Moore CP: Microbial isolates of the normal equine eye. Equine Vet J S2:138–140, 1983.
  4. Andrew SE, Nguyen A, Jones GL, et al: Seasonal effects on the aerobic bacterial and fungal conjunctival flora of normal Thoroughbred brood mares in Florida. Vet Ophthalmol 6(1):45–50, 2003. PUBMED Abstract
  5. Cattabiani F, Cabassi E, Allodi C, et al: Bacterial flora of the conjunctival sac of the horse. Ann Sclavo 18(1):91–119, 1976. PUBMED Abstract
  6. Gemensky-Metzler AJ, Wilkie DA, Kowalski JJ, et al: Changes in bacterial and fungal ocular flora of clinically normal horses following experimental application of topical antimicrobial or antimicrobial-corticosteroid ophthalmic preparations. Am J Vet Res 66(5):800–811, 2005. PUBMED Abstract
  7. Samuelson DA, Andresen TL, Gwin RM: Conjunctival fungal flora in horses, cattle, dogs, and cats. J Am Vet Med Assoc 184:1240–1242, 1984. PUBMED Abstract
  8. Rosa M, Cardozo LM, da Silva Pereira J, et al: Fungal flora of normal eyes of healthy horses from the state of Rio de Janeiro, Brazil. Vet Ophthalmol 6(1):51–55, 2003. PUBMED Abstract
  9. Moore CP: Bacterial and fungal isolates from Equidae with ulcerative keratitis. J Am Vet Med Assoc 182(6):600–603, 1983. PUBMED Abstract
  10. McLaughlin SA: Pathogenic bacteria and fungi associated with extraocular disease in the horse. J Am Vet Med Assoc 182(3):241–242, 1983. PUBMED Abstract
  11. Brooks DE, Andrew SE, Biros DJ, et al: Ulcerative keratitis caused by beta-hemolytic Streptococcus equi in 11 horses. Vet Ophthalmol 3(2-3):121–125, 2000. PUBMED Abstract
  12. Da Silva Curiel JM, Murphy CJ, Jang SS, et al: Nutritionally variant streptococci associated with corneal ulcers in horses: 35 cases (1982-1988). J Am Vet Med Assoc 197(5):624–626, 1990. PUBMED Abstract
  13. Andrew SE, Brooks DE, Smith PJ, et al: Equine ulcerative keratomycosis: visual outcome and ocular survival in 39 cases (1987-1996). Equine Vet J 30(2):109–116, 1998. PUBMED Abstract
  14. Ball MA, Rebhun WC, Gaardner JE, et al: Evaluation of itraconazole-dimethyl sulfoxide ointment for treatment of keratomycosis in nine horses. J Am Vet Med Assoc 211(2):199–203, 1997. PUBMED Abstract
  15. Grahn B, Wolfer J, Keller C, et al: Equine keratomycosis: clinical and laboratory findings in 23 cases. Vet Comp Ophthalmol 3(1):2–7, 1993.
  16. Barton MH: Equine keratomycosis. Compend Contin Educ Pract 14:936–944, 1992.
  17. Beech J, Sweeney CR: Keratomycosis in 11 horses. Equine Vet J S2:39–44, 1983.
  18. Gaarder JE, Rabhun WC, Ball MA, et al: Clinical appearances, healing patterns, risk factors, and outcomes of horses with fungal keratitis: 53 cases (1978-1996). J Am Vet Med Assoc 213(1):105–112, 1998. PUBMED Abstract
  19. Moore CP, Collins BK, Fales WH: Antimicrobial susceptibility patterns for microbial isolates associated with infectious keratitis in horses: 63 cases (1986-1994). J Am Vet Med Assoc 207:928–933, 1995. PUBMED Abstract
  20. Coad CT, Robinson NM, Wilhelmus KR: Antifungal sensitivity testing for equine keratomycosis. Am J Vet Res 46:676–678, 1985. PUBMED Abstract
  21. Brooks DE, Andrew SE, Dillavou CL, et al: Antimicrobial susceptibility patterns of fungi isolated from horses with ulcerative keratomycosis. Am J Vet Res 59(2):138–142, 1998. PUBMED Abstract
  22. Kern TJ, Brooks DE, White MM: Equine keratomycosis: current concepts of diagnosis and therapy. Equine Vet J S2:22–38, 1983.
  23. Moore CP: Eyelid and nasolacrimal disease. Vet Clin North Am Equine Pract 8(3):499–519, 1992. PUBMED Abstract
  24. Hughes DE, Pugh GWJ: Isolation and description of a Moraxella from horses with conjunctivitis. Am J Vet Res 31:457–462, 1970. PUBMED Abstract
  25. Gilger BC, Stoppini R: Diseases of the eyelids, conjunctiva, and nasolacrimal system. In Gilger BC, editor: Equine ophthalmology, St Louis, 2005, Elsevier, pp 107–156.
  26. Lavach JD: Large animal ophthalmology, St Louis, 1990, Mosby.
  27. Connole M: Equine phycomycosis. Aust Vet J 49:214–215, 1973. PUBMED Abstract
  28. Singh T: Studies on epizootic lymphangitis. Indian J Vet Sci 36:45–59, 1966.
  29. Stiles J: Ocular manifestations of systemic disease. Part 3. The horse. In Gelatt KN, editor: Veterinary ophthalmology, ed 3, Philadelphia, 1999, Lippincott, Williams & Wilkins, pp 1473–1492.
  30. Pusterla N, Watson JL, Wilson WD, et al: Cutaneous and ocular habronemiasis in horses: 63 cases (1988-2002). J Am Vet Med Assoc 222(7):978–982, 2003. PUBMED Abstract
  31. Mohamed FH, Abu Samra MT, Ibrahim KE, et al: Cutaneous habronemiasis in horses and domestic donkeys (Equus asinus asinus). Rev Ele Med Vet Pays Trop 42(4):535–540, 1990. PUBMED Abstract
  32. Andrew SE, Willis AM: Diseases of the cornea and sclera. In Gilger BC, editor: Equine ophthalmology, St Louis, 2005, Elsevier, pp 157–251.
  33. Edelhauser HF, Ubels JL: Cornea and sclera. In Kaufman PL, Alm A, editors: Adler's physiology of the eye, ed 10, St Louis, 2003, Mosby, pp 47–114.
  34. Cutler TJ: Corneal epithelial disease. Vet Clin North Am Equine Pract 20:319–343, 2004. PUBMED Abstract
  35. Welch PM, Gabal M, Betts DM, et al: In vitro analysis of antiangiogenic activity of fungi isolated from clinical cases of equine keratomycosis. Vet Ophthalmol 3(2/3):145–152, 2000. PUBMED Abstract
  36. Rashid A, Mubarak A, Hussain A: Babesiosis in equines in Pakistan: a clinical report. Vet Ital 45(3):391–395, 2009. PUBMED Abstract
  37. Collinson PN, O'Reilly JL, Ficorilli N, et al: Isolation of equine herpesvirus type 2 (equine gamma herpesvirus 2) from foals with keratoconjunctivitis. J Am Vet Med Assoc 205(2):329–331, 1994. PUBMED Abstract
  38. Kershaw O, von Oppen T, Glitz F, et al: Detection of equine herpesvirus type 2 (EHV-2) in horses with keratoconjunctivitis. Virus Res 80(1-2):93–99, 2001. PUBMED Abstract
  39. Miller TR, Gaskin JM, Whitley RD, et al: Herpetic keratitis in a horse. Equine Vet J 17(suppl 10):15–17, 1990. PUBMED Abstract
  40. Borchers K, Ebert M, Fetsch A, et al: Prevalence of equine herpesvirus type 2 (EHV-2) DNA in ocular swabs and its cell tropism in equine conjunctiva. Vet Microbiol 118(3-4):260–266, 2006. PUBMED Abstract
  41. Brooks DE: Inflammatory stromal keratopathies: medical management of stromal keratomalacia, stromal abscesses, eosinophilic keratitis, and band keratopathy in the horse. Vet Clin North Am Equine Pract 20(2):345–360, 2004. PUBMED Abstract
  42. Belknap BE, Barden CA, Yin C, et al: Real time PCR as a diagnostic tool for equine fungal keratitis: a preliminary study. Vet Ophthalmol 8(6):444, 2006.
  43. Clode AB: Therapy of equine infectious keratitis: a review. Equine Vet J 42(Suppl 37):19–23, 2010. PUBMED Abstract
  44. Baker A, Plummer CE, Szabo NJ, et al: Doxycycline levels in preocular tear film of horses following oral administration. Vet Ophthalmol 11(6):381–385, 2008. PUBMED Abstract
  45. Michau TM, Schwabenton B, Davidson MG, et al: Superficial, nonhealing corneal ulcers in horses: 23 cases (1989-2003). Vet Ophthalmol 6(4):291–297, 2003. PUBMED Abstract
  46. Hollingsworth SR: Diseases of the anterior uvea. In Gilger BC, editor: Equine ophthalmology, St Louis, 2005, Elsevier, pp 253–268.
  47. Leiva M, Pe�a T, Armengou L, et al: Uveal inflammation in septic newborn foals. J Vet Intern Med 24(2):391–397, 2010. PUBMED Abstract
  48. Reuss SM, Chaffin MK, Cohen ND: Extrapulmonary disorders associated with Rhodococcus equi infection in foals: 150 cases (1987-2007). J Am Vet Med Assoc 1;235(7):855–863, 2009. PUBMED Abstract
  49. Dwyer A, Gilger BC: Equine recurrent uveitis. In Gilger BC, editor: Equine ophthalmology, St Louis, 2005, Elsevier, pp 285–322.
  50. Gilger BC: Equine recurrent uveitis: the viewpoint from the USA. Equine Vet J 42(Suppl 37):57–61, 2010. PUBMED Abstract
  51. Gilger BC, Salmon JH, Yi NY, et al: Role of bacteria in the pathogenesis of recurrent uveitis in horses from the southeastern United States. Am J Vet Res 69(10):1329–1335, 2008. PUBMED Abstract
  52. Pearce JW, Galle LE, Kleiboeker SB, et al: Detection of Leptospira interrogans DNA and antigen in fixed equine eyes affected with end-stage equine recurrent uveitis. J Vet Diagn Invest 19(6):686–690, 2007. PUBMED Abstract
  53. Nell B, Walde I: Posterior segment diseases. Equine Vet J Suppl Mar(37):69–79, 2010. PUBMED Abstract
  54. Strobel BW, Wilkie DA, Gilger BC: Retinal detachment in horses: 40 cases (1998-2005). Vet Ophthalmol 10(6):380–385, 2007. PUBMED Abstract
  55. Douglas LC, Yi NY, Davis JL, et al: Ocular toxicity and distribution of subconjunctival and intravitreal rapamycin in horses. J Vet Pharmacol Ther 31(6):511–516, 2008. PUBMED Abstract
  56. Scagliotti RH: Comparative neuro-ophthalmology. In Gelatt KN, editor: Veterinary ophthalmology, ed 3, Philadelphia, 1999, Lippincott, Williams & Wilkins, pp 1307–1400.
  57. Oliver JE, Lorenz MD, Kornegay JN: Handbook of veterinary neurology, ed 3, Philadelphia, 1997, Saunders.
  58. Newton SA: Suspected bacterial meningoencephalitis in two adult horses. Vet Rec 142(24):665–669, 1998. PUBMED Abstract
  59. Borges AS, Nicoletti JL, Thomassian A, et al: Peripheral vestibular disease associated with temporohyoid osteoarthropathy in a horse. Ciencia Rural 33(3):579–582, 2003.
  60. Power HT, Watrous BJ, De Lahunta A: Facial and vestibulocochlear nerve disease in six horses. J Am Vet Med Assoc 183(10):1076–1080, 1983. PUBMED Abstract
  61. Firth EC: Vestibular disease, and its relationship to facial paralysis in the horse: a clinical study of 7 cases. Aust Vet J 53(12):560–565, 1977. PUBMED Abstract
  62. Raphel CF: Brain abscess in three horses. J Am Vet Med Assoc 180(8):874–877, 1982. PUBMED Abstract
  63. Newton SA: Suspected bacterial meningoencephalitis in two adult horses. Vet Rec 142(24):665–669, 1998. PUBMED Abstract
  64. Mayhew IG, Washbourne JR: A method of assessing auditory and brainstem function in horses. Br Vet J 146(6):509–518, 1990. PUBMED Abstract
  65. Marshall AE, Byars TD, Whitlock RH, et al: Brainstem auditory evoked response in the diagnosis of inner ear injury in the horse. J Am Vet Med Assoc 178(3):282–286, 1981. PUBMED Abstract
  66. Firshman AM, Hayden DW, Valberg SJ, et al: Horner's syndrome associated with fungal mediastinitis in a horse. Equine Vet Educ 15(2):82–85, 2003.
  67. Bacon CL, Davidson HJ, Yvorchuk K, et al: Bilateral Horner's syndrome secondary to metastatic squamous cell carcinoma in a horse. Equine Vet J 28(6):500–503, 1996. PUBMED Abstract
  68. Milne JC: Malignant melanoma causing Horner's syndrome in a horse. Equine Vet J 18(1):74–75, 1986. PUBMED Abstract
  69. Firth EC: Horner's syndrome in the horse: experimental induction and case report. Equine Vet J 10:9, 1978. PUBMED Abstract
  70. Craig DR, Shivy DR, Pankowski RL, et al: Esophageal disorders in 61 horses: results of nonsurgical and surgical management. Vet Surg 18(6):432–438, 1989. PUBMED Abstract
  71. Sweeney RW, Sweeney CR: Transient Horner's syndrome following routine intravenous injections in two horses. J Am Vet Med Assoc 185:802–803, 1984. PUBMED Abstract
  72. Owen RR: Epistaxis prevented by ligation of the internal carotid artery in the guttural pouch. Equine Vet J 6(4):143–149, 1974. PUBMED Abstract
  73. Hahn CN: Horner's syndrome in horses. Equine Vet Educ 15(2):86–90, 2003.
  74. Green SL, Cochrane SM, Smith-Maxie L: Horner's syndrome in ten horses. Can Vet J 33:330–333, 1992. PUBMED Abstract
  75. Simoens P, Lauwers H, De Muelenare C, et al: Horner's syndrome in the horse: a clinical, experimental and morphological study. Equine Vet J 10:62–65, 1990. PUBMED Abstract
  76. Scott EA, Duncan JR, McCormack JE: Cryptococcosis involving the postorbital area and frontal sinus in a horse. J Am Vet Med Assoc 165(7):626–627, 1974. PUBMED Abstract
  77. Al-Ani FK: Epizootic lymphangitis in horses: a review of the literature. Rev Sci Tech 18(3):691–699, 1999. PUBMED Abstract
  78. Gabal MA, Mohammed KA: Use of enzyme-linked immunosorbent assay for the diagnosis of equine histoplasmosis farciminosi (epizootic lymphangitis). Myopathologia 91(1):35, 1985. PUBMED Abstract
  79. Gabal MA: The effect of amphotericin-B, 5-fluorocytosine and nystatin on Histoplasma farciminosum in vitro. Zentralbl Veterinarmed 31(1):46–50, 1984. PUBMED Abstract
  80. Hatziolos BS, Sass B, Albert TF: Ocular changes in a horse with gutturomycosis. J Am Vet Med Assoc 167:51–54, 1975. PUBMED Abstract
  81. Uhlinger C: Leukoencephalomalacia. Vet Clin North Am Equine Pract 13(1):13–20, 1997. PUBMED Abstract
  82. MacKay RJ, Granstrom DE, Saville WJ, et al: Equine protozoal myeloencephalitis. Vet Clin North Am Equine Pract 16(3):405–425, 2000. PUBMED Abstract
  83. Madigan JE, Pusterla N: Ehrlichial diseases. Vet Clin North Am Equine Pract 16(3):487–500, 2000. PUBMED Abstract
  84. MacKay RJ: Equine protozoal myeloencephalitis. Vet Clin North Am Equine Pract 13(1):79–96, 1997. PUBMED Abstract
  85. Finno CJ, Eaton JS, Aleman M, Hollingsworth SR: Equine protozoal myeloencephalitis due to Neospora hughesi and equine motor neuron disease in a mule. Vet Ophthalmol 13(4):259–265, 2010. PUBMED Abstract
  86. Sabourin CL, Kusewitt DF, Applegate LA, et al: Expression of fibroblast growth factors in ultraviolet radiation–induced corneal tumors and corneal tumor cell lines from Monodelphis domestica. Mol Carcinog 7:197–205, 1993. PUBMED Abstract
  87. Sippel WL, Cooperrider DE, Gainer JH: Equine piroplasmosis in the United States. J Am Vet Med Assoc 141:694–698, 1962. PUBMED Abstract
  88. Kuttler KL, Zaugg JL, Gipson CA: Imidocarb and parvaquone in the treatment of piroplasmosis (Babesia equi) in equids. Am J Vet Res 48(11):1613–1616, 1987. PUBMED Abstract
  89. Rashid A, Mubarak A, Hussain A: Babesiosis in equines in Pakistan: a clinical report. Vet Ital 45(3):391–395, 2009. PUBMED Abstract
  90. Dubey JP, Thulliez P, Romand S, et al: Serologic prevalence of Toxoplasma gondii in horses slaughtered for food in North America. Vet Parasitol 86(4):235–238, 1999. PUBMED Abstract
  91. Chhabra MB, Gautam OP: Antibodies to Toxoplasma gondii in equids in north India. Equine Vet J 12(3):146–148, 1980. PUBMED Abstract
  92. Alexander CS, Keller H: Atiologie und Vorkommen der periodischen augenentzundung des pferdes iim Raum Berlin. Tierarztl Prax 18:623–627, 1990.
  93. Turner CB, Savva D: Detection of Toxoplasma gondii in equine eyes. Vet Rec 129(6):128, 1991. PUBMED Abstract
  94. McDonald DR, Cleary DJ: Toxoplasmosis in the equine. Southwest Vet 23:213–214, 1970.
  95. Eugster AK, Joyce JR: Prevalence and diagnostic significance of Toxoplasma gondii antibodies in horses. Vet Med Small Anim Clin 71:1469–1473, 1976. PUBMED Abstract
  96. Moore CP, Sarazan RD, Whitley RD, et al: Equine ocular parasites: a review. Equine Vet J S2:76–85, 1983.
  97. Munger RJ: Equine onchocercal keratoconjunctivitis. Equine Vet J S2:76–85, 1983.
  98. Cello RM: Ocular onchocerciasis in the horse. Equine Vet J 3:148–154, 1971. PUBMED Abstract
  99. Schmidt GM, Krehbiel JD, Coley SC, et al: Equine ocular onchocerciasis: histopathologic study. Am J Vet Res 43:1371–1375, 1982. PUBMED Abstract
  100. Attenburrow DP, Donnelly JJ, Soulsby EJ: Periodic ophthalmia (recurrent uveitis) of horses: an evaluation of the aetiological role of microfilariae of Onchocerca cervicalis and the clinical management of the condition. Equine Vet J S2:48–56, 1983.
  101. Pollitt CC, Holdsworth PA, Kelly WR, et al: Treatment of equine onchocerciasis with ivermectin paste. Aust Vet J 63(5):152–156, 1986. PUBMED Abstract
  102. Rebhun WC, Mirro EJ, Georgi ME, et al: Habronemic blepharoconjunctivitis in horses. J Am Vet Med Assoc 179(5):469–472, 1981. PUBMED Abstract
  103. Gasthuys FM, van Heerden M, Vercruysse J: Conjunctival habronemiasis in a horse in Belgium. Vet Rec 154(24):757–758, 1994.
  104. Read RA, King MC, du Preez PM: Ulcerative keratitis associated with suspected habronemiasis conjunctival granuloma. Equine Vet Educ 8(4):184–186, 1996.
  105. Glaze MB: Equine adnexal habronemiasis. Equine Vet J S2:71–73, 1983.
  106. Herd RP, Donham JC: Efficacy of ivermectin against cutaneous Draschia and Habronema infection (summer sores) in horses. Am J Vet Res 42:1953–1955, 1981. PUBMED Abstract
  107. Lavach JD: Conjunctiva, limbus, episclera and sclera. In Barnett KC, Crispin SM, Lavach JD, et al, editors: Equine ophthalmology: an atlas and text, ed 2, Edinburgh, 2004, Saunders, pp 93–106.
  108. Porter MB, Long MT, Getman LM, et al: West Nile virus encephalomyelitis in horses: 46 cases (2001). J Am Vet Med Assoc 222(9):1241–1247, 2003. PUBMED Abstract
  109. Miyashiro MJ, Yee RW, Patel G, et al: Lyme disease associated with unilateral interstitial keratitis. Cornea 18(1):115–116, 1999. PUBMED Abstract
  110. Madigan JE: Equine ehrlichiosis. Vet Clin North Am Equine Pract 9(2):423–428, 1993. PUBMED Abstract
  111. Nyindo MB, Ristic M, Lewis GEJ, et al: Immune response of ponies to experimental infection with Ehrlichia equi. Am J Vet Res 39(1):15–18, 1978. PUBMED Abstract
  112. Summerhays GE, Mantell JA: Ultrasonography as an aid to diagnosis and treatment of a retrobulbar hydatid cyst in a horse. Equine Vet Educ 7(1):39–42, 1995.
  113. Barnett KC, Cottrell BD, Rest JR: Retrobulbar hydatid cyst in the horse. Equine Vet J 20:136–138, 1988. PUBMED Abstract